MHC Tetramers

MHC Tetramers have emerged as an important tool for characterization of the specificity and phenotype of T cell immune response. T cell receptors (TCRs) recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. LabForce offers tetramers and biotinylated monomers for many human and mouse alleles and for a variety of peptide targets. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet™ 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy.